Growing the research evidence on e cigarettes by Research at CRUK Medium Electronic cigarettes (e cigarettes) are sometimes called e cigs, vapes, vape pens, and electronic nicotine delivery systems (ENDS). E cigarettes come in many shapes and sizes. Most e cigarettes contain nicotine. Get the facts about e cigarettes, The Side Effects and Cancer Risk Associated with Vaping Clearing the Air: The Harsh Reality of Vaping and Smokeless Products Leading to Cancer E Cigarette Smoke Causes Lung Cancer in Mice NYU Langone News Can vaping cause cancer? The evidence suggests it might.